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425 SOUTH SECOND STREET, 55401 Minneapolis

425 SOUTH SECOND STREET, 55401 Minneapolis
Close to the banks of the Mississippi River, the hotel is within easy reach of Minneapolis’ superb cultural offerings and within walking distance of the Mill City Museum, the Stone Arch Bridge and the Guthrie Theatre. The convention centre is less than 3 kilometres away.
Residence Inn Minneapolis Downtown at The Depot has suites with separate living,kitchen,sleeping areas. Our extended stay hotel is close to the Guthrie Theatre, Target Field, US Bank Stadium and Light Rail. Enjoy an unforgettable stay at the Residence Inn Depot, located in the beautiful Mississippi Riverfront District in Downtown Minneapolis. Surround yourself with the rich history of the Twin Cities. Experience art and history as you stroll across the Stone Arch Bridge overlooking St. Anthony Falls, catch a show at the Armory, Guthrie Theater, or check out the Mill City Museum. Our hotel is conveniently located near the skyway system and just a few blocks from your favorite Minneapolis sports teams. Target Field, Target Center, Huntington Bank Stadium and US Bank Stadium are all within walking distance of the Residence Inn. Our hotel is also located just 11 miles from the Mall of America. Please your taste buds with a variety of food from Milwaukee Road, located inside the adjoining Renaissance Minneapolis Hotel, The Depot. Let us keep you comfortable and relaxed in one of our spacious suites with great amenities while you explore this unique area of downtown.
The neighborhood contains former flour mills from the days when Minneapolis was the flour milling capital of the world. The area has several cultural institutions, including the Guthrie Theater, the Mill City Museum as well as the MacPhail Center.
The hotel has undergone a self-inspection regarding its enhanced protective measures.
Earliest check-in
04:00 PM
Latest check-out
11:00 AM
This hotel measures and reports its environmental footprint - including carbon, water and waste through the HRS Green Stay assessment based on the Sustainable Hospitality Alliance's HCMI and HWMI methodologies. The grades below reflect the hotel’s performance per occupied room night, measured against Green Stay’s thresholds for its regions.
The Green Stay indicator reflects reported data from hotels; it is not an environmental certification.
Carbon dioxide
B
21 kg CO2 / night
Water
B
420 liter / night
Waste
D
8.8 kg / night
Figures reflect data reported by the hotel for 2025.
Calculations include Scope 1, 2 and Partial Scope 3. They exclude upstream supply chain (Scope 3.2-3.14) and are not a full life cycle assessment (LCA). HRS performs plausibility and anomaly checks and does not independently verify or audit sustainability data provided by the hotels.
Sustainability Programs
Serve 2424